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Examining pathways between structural stigma and tobacco use: a comparison among young adults living in the United States by sexual orientation and gender identity

Abstract

Background

Sexual and gender minority young adult (SGM YA) populations use tobacco at higher rates than their non-SGM YA peers. Prior studies have identified significant correlations between interpersonal stigma and tobacco use, yet structural stigma may also influence tobacco use among SGM YA. This study aimed to assess the indirect effects of structural stigma on current tobacco use among SGM YA and non-SGM YA via depletion of economic resources, interpersonal discrimination, and perceived psychological stress.

Methods

Structural Equation Modeling was used to conduct a secondary data analysis from a cross-sectional parent study. Eligible participants were 18–35 years old and currently residing in the U.S. (N = 2,649). Current use of combustible cigarettes and nicotine vapes was our dependent variable. Our independent variable of interest, structural stigma, was a latent variable comprised of three state-level indicator items: Attitudes toward SGM people, SGM protective policies (absence of), and SGM discriminatory policies (introduced or passed in 2022). We assessed three mediators of interest: Depletion of economic resources was a latent variable, which included two indicator items: food insecurity and financial strain. Interpersonal discrimination and perceptions of psychological stress were also assessed. Covariates included race/ethnicity, age, and educational attainment.

Results

Structural stigma was indirectly associated with current tobacco use via depletion of economic resources for SGM YA, but not non-SGM YA. Structural stigma was not indirectly associated with current tobacco use via interpersonal discrimination or psychological stress for either group.

Conclusions

Future tobacco intervention research should consider the role of structural stigma when working with SGM YA; specifically, how interventions promoting economic stability may influence tobacco use and cessation in this population.

Background

Smoking remains one of the leading causes of preventable death in the United States (US) accounting for approximately 480,000 deaths in the US each year [1]. Sexual and gender minority young adult (SGM YA) populations use tobacco at significantly higher rates than their non-SGM YA peers, with disparities beginning in adolescence and continuing into young adulthood [2,3,4]. The Minority Stress Model (MSM) purports that the unique multilevel stressors experienced by SGM YA lead them to engage in risky health behaviors (such as nicotine vape and cigarette use) at higher rates [5]. The MSM specifically suggests that distal minority stressors, such as discrimination and discriminatory policies, lead to proximal minority stressors or internalized processes such as internalized queerphobia and perceived discrimination, which in turn can engender negative health outcomes such as tobacco use. Prior studies have identified significant correlations between minority stressors and tobacco use; however, most of these studies have focused on individual and interpersonal stigma, including experiences of internalized queerphobia and perceived discrimination [6]. Yet, structural or societal-level stressors may also influence tobacco use among SGM YA.

Structural stigma has been defined as “societal-level conditions, cultural norms, and institutional policies that constrain the opportunities, resources, and wellbeing” of minoritized populations [7]. In 2023, there were 510 anti-SGM bills introduced in state legislatures in the US, a three-fold increase from the previous year. This trend is continuing in 2024, with 527 anti-SGM bills introduced into state legislatures to date. These bills span a variety of issues, from laws prohibiting free speech and expression to those limiting healthcare access for SGM people [8]. A recent narrative review of quantitative studies examining the effect of structural stigma on SGM individuals health found that, to date, 14 studies have examined how structural stigma is associated with tobacco use among SGM individuals [9]. These studies examined a diverse set of exposures and reported mixed results. Seven studies found that protective structural factors (e.g., community supportiveness, anti-discrimination laws) decreased rates of smoking among SGM youth and young adults [10,11,12,13,14,15,16]. An additional three studies found that greater levels of structural stigma (e.g., negative community attitudes, discriminatory policies) were associated with higher rates of tobacco use [17,18,19]. The remaining studies demonstrated mixed effects. For example, a study of US adults indicated that legalization of same sex relationships led to higher smoking among women in same sex households but not men [20]. None of these studies examined mediating mechanisms by which structural stigma may influence tobacco use among SGM YA.

Ecological models of population health hypothesize that upstream factors, such as living in SGM discriminatory contexts (i.e., experiencing structural stigma) deplete the social and economic resources available to SGM people by legitimizing and institutionalizing discriminatory practices (e.g., employment and wage discrimination) and increasing interpersonal discrimination experiences. These factors, in turn, contribute to individual-level economic instability (e.g., poverty status, food insecurity), ultimately leading to increased psychological stress and coping behaviors (e.g., smoking) [21]. Previous work supports this hypothesis, though this work is sparse, with only 10% of studies examining structural stigma and its relation to health having examined mediating effects [9]. The extant literature has predominantly explored interpersonal and individual-level minority stress (e.g., discrimination experiences, internalized queerphobia) as candidate mechanisms between structural stigma and mental health outcomes [9]. Generally, these studies find that SGM youth and adults living in states with high structural stigma (vs. low structural stigma) experience greater interpersonal and internalized minority stress, which is associated with poor mental health. More recently, Romm and colleagues examined 7 policy categories (relationship/parent recognition, nondiscrimination, religious exemptions, LGBTQ youth, healthcare, criminal justice, gender identity documents) and their direct and indirect effects on tobacco use. The authors found that residing in states with limited relationship/parent recognition policies indirectly predicted higher odds of e-cigarette use through mental health; weaker nondiscrimination policies indirectly predicted using more tobacco products through internalized stigma; and negative healthcare policies indirectly predicted higher odds of cigarette and any tobacco use through community connectedness [22]. Although this study considered mediating mechanisms suggested by the MSM (i.e., internalized stigma and community connectedness), it did not consider how structural stigma may influence tobacco use via socioeconomic determinants such as income and food insecurity which have previously been shown to be among the strongest correlates of tobacco use among adults generally [23, 24]. No studies have examined economic factors as candidate mechanisms between structural stigma and poor health outcomes. However, in one study of gay men, individuals living in states with greater structural stigma (defined as prejudicial attitudes) reported decreased wages, and prejudice coming from their workplace managers was found to mediate this association [25]. Together, this body of theoretical and empirical research suggests that structural stigma may be influencing health outcomes among SGM people through several mediating mechanisms.

Purpose of the study

This study builds on the limited evidence testing the mechanisms through which structural stigma influences SGM YA health behaviors. We aimed to assess the indirect effects of structural stigma on current tobacco use among SGM YA and cisgender and heterosexual YA (non-SGM YA). Consistent with ecological and minority stress models, we examined the potential pathways that may create and exacerbate disparities in tobacco use. Specifically, we were interested in how the depletion of economic resources, interpersonal discrimination, and perceived psychological stress might mediate the relationship between structural stigma and current tobacco use. To more strongly establish causal inferences about the influence of structural stigma on health, leading scholars recommend that studies examine whether structural stigma affects health among the stigmatized group (i.e., SGM YA), but not the non-stigmatized group (i.e., non-SGM YA). If the relationship between structural stigma and health is observed only in the stigmatized group, this increases confidence that this result is due to structural stigma itself [26]. Therefore, in the present study we included non-SGM YA as a comparison group to examine the specific effects of structural stigma on tobacco use among SGM and non-SGM YA.

Methods

Study design

This study is a secondary data analysis from a larger, cross-sectional parent study meant to evaluate the effectiveness of tobacco public health education messages among young adults aged 18–35 years old. This age group is particularly vulnerable to tobacco use. Emerging young adults (age 18–24 years old) are considered in a period of transition, exploration, and risk-raking, which may include tobacco use. While established young adults (age 25–35 years) continue to experience substantial life transitions, including financial instability and independence, which may influence tobacco use. Given that quitting tobacco use before age 35 years prevents significant reduction in years of life lost due to tobacco-related health harms, studies that can identify potential intervention points to reduce tobacco use among young adults aged 18–35 years old is critical for population health promotion.

Participant completed surveys between September and November 2022. Prolific (https://www.prolific.co/), an online subject recruitment platform, was used to recruit participants, due to its large access to US nationals ( 38.000), its base of young adults (approximately one-third are < 35 years old), and its effectiveness for reaching minoritized populations, including SGM people. The parent study purposively oversampled SGM people, people who smoke cigarettes, and people who vape nicotine. We also sampled proportionally for each racial/ethnic group per US Census 2020 estimates. Potential participants were prescreened via Prolific. Those who met the eligibility criteria of being aged 18–35 years old and currently residing in the US were directed to an online consent form. After consenting, participants (N = 2,857) were directed to a Qualtrics survey. They received $4.50 for participating. The parent study was approved by The Ohio State University Institutional Review Board (2021C0020).

Measures

Measures are described in detail in Table 1. Our sample included two subgroups of interest: SGM YA and non-SGM YA. We used two items to assess participants’ self-reported sexual identity group and self-reported gender identity group. Individuals identifying with sexual or gender minority identity groups (e.g., lesbian, gay, bisexual, queer, transgender, nonbinary) were defined as SGM; those identifying as both cisgender and heterosexual were defined as non-SGM individuals. Our dependent variable, current tobacco use, was a latent variable comprised of two indicator items: past 30-day use of combustible cigarettes or past 30-day use of nicotine vapes. Our independent variable of interest, structural stigma, was a latent variable comprised of three state-level indicator items: Attitudes toward SGM people [27], SGM protective policies (absence of) [28], and SGM discriminatory policies (introduced or passed in 2022) [29]. Policies were analyzed at the state-level, with scores indicating the number of areas in which there was absence of protective policies for SGM people and the number of categories in which there had been introduced and enacted legislation targeting SGM rights. Attitudes were aggregated at the regional level, with higher than the national average anti-SGM sentiments in 5 categories adding to the overall score. The same regional score was prescribed to each state within the region. These scores were then added and assigned to participants by their state of residence. Data was taken from the ACLU rather than other sources because we wanted to examine the influence of contemporary policy changes, including the introduction of bills as well as polices that were adopted, which is better extrapolated from the ACLU. More details are provided in Table 1 (additional details by state are provided in Supplementary Table 1). We assessed three mediators of interest: Depletion of economic resources was a latent variable, which included two indicator items. The first assessed past 12-month experiences of food insecurity and the second assessed perceived financial strain. Interpersonal discrimination was assessed using the everyday discrimination scale, which assesses self-reported frequency of daily discrimination experiences in social situations [30]. We used a general measure of discrimination rather than assessing SGM-specific discrimination experiences so that we could assess the influence of this hypothesized mediator on tobacco use among non-SGM YA. Finally, the four-item Perceived Stress Scale was used to assess individual perceptions of psychological stress [31]. Covariates included race/ethnicity, age, and educational attainment.

Table 1 Survey measures

Analysis

A comprehensive investigation was conducted using Structural Equation Modeling (SEM) to examine the association between structural stigma and current tobacco use, including combustible cigarettes and nicotine vapes. This study employed SEM with Maximum Likelihood Estimation (MLE) to examine the relationship between multiple variables, considering their direct and indirect effects on current tobacco use. Structural stigma was our predictor variable. Depletion of economic resources (financial strain and food insecurity), interpersonal discrimination, and perceived psychological stress were our mediating variables. All SEM analyses were performed in R (V 4·2·2) using the Lavaan package (0·6–16). We used listwise detection to handle missing data, this removes cases with any missing values in our variables of interest from the analysis. After removing 183 individuals who were over the age of 35 and an additional 7 individuals who did not answer our sexual orientation questions, no missing values were detected. Modification indices were inspected for significant areas of model misfit; however, none were detected so model adjustment was not necessary. Model fit was evaluated using the following fit indices: Comparative Fit Index (CFI), Root Mean Square Error of Approximation (RMSEA), and Standardized Root Mean Squared Residual (SRMR). Indicators of acceptable model fit were considered as CFI > 0·9, RMSEA < 0·06, and SRMR < 008. An alpha of ·05 was used to indicate statistically significant pathways between constructs. We conducted Confirmatory Factor Analysis (CFA) to examine whether our predictor and mediating variables would best work as latent variables. As seen in Table 2, the CFA indicated that our three predictor variables fit best on a single factor, structural stigma, for both the non-SGM and SGM YA. Our measures of economic depletion also loaded onto a single latent variable as did our two outcome variables (combustible cigarettes and nicotine vapes). The fit of the CFA for SGM YA and non-SGM YA was acceptable, RMSEA = 0.003, CFI = 0.99, SRMR = 0.01 and RMSEA = 0.02, CFI = 0.99, SRMR = 0.01 and respectively.

Table 2 Standardized coefficients for CFA

Results

Sample description

As shown in Table 3, across both groups (n = 1,281 SGM YA and n = 1,368 non-SGM YA), most participants were White (64% SGM YA, 55% non-SGM YA) and had similar current use of nicotine vapes (35% SGM YA, 36% non-SGM YA). More non-SGM than SGM YA were Black, Indigenous, and People of Color (BIPOC; 45% vs. 36%), aged 25–35 years (31% vs. 26%), held a four-year degree or higher (53% vs. 47%), and currently smoked combustible cigarettes (31% vs. 26%). SGM YA reported greater financial strain (M = 5·35 vs. M = 4·62), food insecurity (M = 4·24 vs. M = 3·62), interpersonal discrimination (M = 11·98 vs. 10·47), and perceived stress (M = 8·61 vs. 7·26) compared to non-SGM YA.

Table 3 Descriptive statistics for study variables

Preliminary analyses

Bivariate correlations among all measured variables are presented in Table 4. Among non-SGM YA, our indicator variables of structural stigma (attitudes towards SGM individuals, SGM discriminatory bills, absence of SGM protective policies) were not significantly associated with our outcome variables (current combustible cigarette and nicotine vape use). Other than financial strain (r = 0·06, p < 0·05), our indicator variables of structural stigma were not related to mediators nor covariates. Given that our three variables of structural stigma were not independently associated with our outcome variables, we examined them as a single composite variable of structural stigma. However, there was a significant positive intercorrelation between our measures of financial strain, food insecurity, interpersonal discrimination, and perceived stress. Finally, all covariates (age, race, and education) were significantly associated with our outcome variables. For race, being a race other than White was associated with increased current use of combustible cigarettes and nicotine vapes. For education, having less than a four-year degree was associated with increased current use of combustible cigarettes and nicotine vapes. For age, being between 25 and 35 years was associated with greater current use of combustible cigarettes, while being between 18 and 24 years was associated with greater current use of nicotine vapes. Latinx ethnicity was not significantly associated with our outcome variables among non-SGM YA.

Table 4 Correlation among measured variables, heterosexual
Table 4 Correlation among measured variables, SGM

Among SGM YA, like non-SGM YA, none of our indicator variables of structural stigma were directly associated with current use of combustible cigarettes or nicotine vapes. However, discriminatory bills under consideration were positively associated with financial strain and enacted discriminatory bills were positively associated with food insecurity. There was a significant positive intercorrelation between our measures of financial strain, food insecurity, experiences of interpersonal discrimination, and perceived stress. Finally, like non-SGM YA, being between 25 and 35 years was associated with greater current use of combustible cigarettes, while being between 18 and 24 years was associated with greater current use of nicotine vapes for SGM YA. No other covariates were associated with outcome variables among the SGM YA group.

Model fit

SEM was used to test the hypothesized model (Figs. 1 and 2), examining the indirect effects of structural stigma (i.e., discriminatory attitudes, discriminatory policies, and absence of protective policies) on current tobacco use among subpopulations of SGM and non-SGM YA. Depletion of economic resources (i.e., food insecurity and financial strain) perceived interpersonal discrimination experiences, and psychological stress were assessed as mediators between structural stigma and current tobacco use. The data fit for both SGM YA (χ2 = 267·5, p < 0·05, CFI = 0·92, SRMR = 0·05, RMSEA = 0·06; Fig. 1) and non-SGM YA (χ2 = 234·6, p < 0·05, CFI = 0·95, SRMR = 0·05, RMSEA = 0·05; Fig. 2).

Fig. 1
figure 1

Structural equation model assessing theoretically informed pathways between structural stigma and current tobacco use among sexual and gender minority (SGM) young adults. Indirect effects are in paratheses

Fig. 2
figure 2

Structural equation model assessing theoretically informed pathways between structural stigma and current tobacco use among non-SGM young adults. Indirect effects are in paratheses

Table 5 Indirect effects of structural stigma, on current use of combustible cigarettes or nicotine vapes

Pathways between structural stigma and current tobacco use among SGM YA

The final model accounted for 5.8% of the variance in current tobacco use among SGM YA. Structural stigma was indirectly associated with greater current tobacco use through depletion of economic resources for the SGM YA group (β = 0·01, z = 2·16, p < 0·05, Table 5). This indicates that greater structural stigma is associated with greater depletion of economic resources which, in turn, is associated with increased current tobacco use among our sample of SGM YA. As seen in Table 5, the indirect effect of structural stigma via interpersonal discrimination, (β = -0·002, z = -0.46, p > 0·05) and via psychological stress, (β = -0·002, z = 1.306, p > 0·05) were not statistically significant.

Pathways between structural stigma and current tobacco use among non-SGM YA

The final model accounted for 11·6% of the variance in current tobacco use for the non-SGM YA group. While structural stigma was significantly associated with depletion of economic resources among non-SGM YA, there was not a significant indirect pathway linking structural stigma and current tobacco use via depletion of economic resources for non-SGM YA (β = 0·005, z = 1.59, p > 0·05). As seen in Table 5, the indirect effect of structural stigma via interpersonal discrimination, (β = 0·000, z = 0.002, p > 0·05) and psychological stress (β = -0·001, z = -1·053, p > 0·05) were also not statistically significant.

Covariate associations with current tobacco use

In terms of covariates, age was significantly associated with current tobacco use for non-SGM YA, indicating that individuals ages 25–35 years were more likely to use tobacco compared to those aged 18–24 years. Additionally, race was associated with current tobacco use only for non-SGM YA, indicating that more BIPOC YA in this group reported current tobacco use more than White YA.

Discussion

Our study is one of the first to assess how structural stigma may influence current tobacco use among SGM and non-SGM YA via theoretically informed pathways. As indicated in Figs. 1 and 2, there was no direct effect of structural stigma on current tobacco use. However, methodological research has indicated that mediation or indirect effects can still be present in the absence of a direct effect and should therefore be examined [32]. Results indicated that structural stigma was indirectly associated with current tobacco use through the depletion of economic resources (increased financial strain and food insecurity) for SGM YA, but not for non-SGM YA. Previous research examining food insecurity among SGM individuals has found that states with Religious Freedom Restoration Acts or “religious freedom” laws allow institutions, including food pantries, to deny services to select community members, such as SGM YA, based on religious beliefs [33]. Such laws may contribute to the higher rates of food insecurity seen in SGM compared to non-SGM individuals [34]. Additionally, a lack of familial support has previously been tied to food insecurity among SGM YA [35, 36]. In states where anti-SGM sentiments are especially high, losing connection with family members can reduce “safety nets” that could support SGM YA prior to accessing community resources such as food pantries. Food insecurity has been linked to tobacco use in a variety of vulnerable populations [24]. Although previous research has indicated that the direction of the association is unclear (i.e., causality cannot be established given that the majority of studies, including the present one, have been cross-sectional in nature), both financial strain and stress have been suggested as possible mechanisms that link food insecurity to tobacco use for both SGM and non-SGM populations [24]. Appetite suppression is another mechanism that has examined in the association between food insecurity and tobacco use (i.e., a physiological effect of nicotine is hunger suppression, whereas nicotine withdrawal causes increased eating) [24]. Longitudinal studies are needed to further examine the directionality of the association between food insecurity and tobacco use. Additionally, states with less protective policy environments, especially those in traditionally conservative states, tend to have lower tobacco taxes which makes these products more accessible as an appetite suppressant [37]. Future research should consider examining the role tobacco taxes play in the association between structural stigma, food insecurity, and tobacco use among SGM YA. Nevertheless, our results indicate depletion of economic resources may be one mechanism by which structural stigma may influence current tobacco use among SGM YA. Given the well documented disparities in tobacco use among SGM YA, future tobacco intervention studies should consider food insecurity and financial strain as points of intervention for this population.

In a recent narrative review examining the role of structural stigma on health outcomes (including behavioral health), a conceptual model was proposed indicating that interpersonal discrimination may mediate the association between structural stigma and behavioral health (i.e., current tobacco use) outcomes [9]. However, our study is one of the first to examine the pathway proposed by this conceptual model (i.e., structural stigmaàinterpersonal discriminationàbehavioral health outcomes). In our study, structural stigma was not indirectly associated with current tobacco use via interpersonal discrimination. This null finding for an indirect pathway between structural stigma and current tobacco use via interpersonal discrimination may be due to construct operationalization. While our structural stigma measure was SGM-specific, our interpersonal discrimination measure assessed perceptions of interpersonal discrimination for any reason (e.g., due to SGM identity, race/ethnicity, religion body size, physical ability, etc.) so that we could assess this construct among non-SGM YA. Additionally, our follow up interpersonal discrimination question indicated that among our SGM YA group, only 9.55% indicated that their discrimination experiences were due to sexual orientation and 27.60% indicated that it was due to gender. Given this small percentage, this could explain why there was no direct association between structural stigma and interpersonal discrimination in this study. However, similar to prior studies [6], we identified a direct association between interpersonal discrimination and current tobacco use. As mentioned previously, longitudinal studies are needed to examine how structural stigma may influence interpersonal discrimination over time and how this, in turn, may influence current tobacco use among SGM YA. This work should include measures assessing SGM-specific interpersonal discrimination, which may be more closely associated with structural stigma.

Our study has limitations, including the use of cross-sectional data and the lack of a sufficient sample size to examine the SGM YA subgroup (e.g., bisexual vs. gay, or by gender identity, see Supplemental Table 2 for additional sexual orientation and gender identity data) as a moderator. Additionally, our measure of attitudes toward sexual minoritized people focused only on sexual minorities and did not include questions regarding gender minorities, which is important given that most discriminatory policies being proposed and enacted restrict the freedoms of gender minority individuals specifically. Furthermore, we were only able to assess combustible cigarette and nicotine vape use the prevalence of other tobacco product use in our sample was too low to meaningfully add these to the analyses. The current study also did not assess frequency or severity of tobacco use, which will be important to assess in the association between structural stigma and tobacco use in future studies. Finally, our indirect effect of structural stigma on current tobacco use for SGM YA via economic depletion, while significant, was small and therefore should be interpreted cautiously. Nevertheless, our study addressed several gaps identified previously in the literature and is one of the few to conduct mediational analyses examining the indirect effects of structural stigma on health outcomes among SGM YA. Previous research [18, 19] indicates a need to examine how structural stigma may indirectly influence tobacco use among SGM individuals, specifically, and our study is one of the first to examine this association as it relates to current tobacco use in SGM YA. Our study also addresses a gap identified in the literature [9] by including a non-SGM YA comparison group. In doing so, we demonstrated that structural stigma is associated with current tobacco use, via depletion of economic resources, for SGM YA only. Given unprecedented increases in legislation targeting SGM individuals’ rights, identifying intervention points to attenuate the negative effects of structural stigma on tobacco use is critical for promoting SGM individuals health across the life course.

Conclusions

In conclusion, although the association between structural stigma and health in general has been well established among SGM individuals, our study is one the first to examine the indirect effects of structural stigma on current tobacco use specifically among a highly vulnerable population, SGM YA. Future tobacco cessation and harm reduction intervention research should consider the role of structural stigma when working with SGM YA; specifically, how interventions promoting economic stability may influence tobacco use and cessation in this population. It will also be important to examine how changes in general attitudes towards SGM individuals and lack of protective policy and discriminatory policy toward SGM individuals influences tobacco use in SGM YA over time, as previous research has indicated that improvements in structural stigma may be associated with improvement in life satisfaction in this population [38].

Data availability

Data and relevant code is available upon reasonable request from the PI (JGP).

Abbreviations

BIPOC:

Black Indigenous and People of Color

CFI:

Comparative Fit index

MLE:

Maximum Likelihood Estimation

RMSEA:

Root Mean Square Error of Approximation

SEM:

Structural Equation Modeling

SGMYA:

Sexual and gender minority young adult

SGM:

Sexual and gender minority

SRMR:

Standardized Root Mean Squared Residual

YA:

Young adults

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Acknowledgements

Thank you to all members of the Practice and Science for LGBTQ+ Health Equity Lab for their contributions to the parent study.

Funding

Research reported in this publication was supported by the National Cancer Institute of the National Institutes of Health and the FDA Center for Tobacco Products under Award Numbers 5T32CA229914 (WF), K99CA260718, and R00CA260718 (PI: JGP). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health or Food and Drug Administration. This study was supported by The Ohio State University (OSU) James-Comprehensive Cancer Center’s Center for Tobacco Research and The OSU College of Public Health.

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W.F.: Conceptualization, Methodology, Formal analysis, Writing– original draft, review and editing. S.S.: Lead Formal Analysis, Writing-original draft. E.J.: Data curation, Project administration, Writing- original draft, review and editing. A.C.E.: Data curation, Project administration, Writing-review and editing. A.T.: Writing-review and editing. E.S.: Writing-review and editing. J.G.P.: Funding Acquisition, Conceptualization, Methodology, Data curation, Project administration, Writing– original draft, review and editing.

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Correspondence to Wilson Figueroa.

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The parent study was approved by The Ohio State University Institutional Review Board, which adheres to the ethical principles for the protection of research participants summarized in the Belmont Report and complies with federal regulations, guidance, and state laws related to human subjects protection, (2021C0020). All participants consented prior to completing the survey.

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The authors declare no competing interests.

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Figueroa, W., Sridhar, S., Jankowski, E. et al. Examining pathways between structural stigma and tobacco use: a comparison among young adults living in the United States by sexual orientation and gender identity. Int J Equity Health 24, 128 (2025). https://doiorg.publicaciones.saludcastillayleon.es/10.1186/s12939-025-02487-2

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