Table 3 Cox proportional hazards analysis of variables associated with LTFU or death among HERE study participants
Explanatory variables | Unadjusted hazard ratio | P-value | Adjusted hazard ratio | P-value |
|---|---|---|---|---|
Demographics | ||||
Age (per 10-year increment) | 1.02 (0.86–1.20) | 0.844 | ||
Gender | ||||
Female | 1.00 | |||
Male | 1.44 (0.88–2.34) | 0.146 | ||
Homelessness Experience | ||||
Never been homeless | 1.00 | |||
Currently homeless | 0.60 (0.30–1.18) | 0.137 | ||
Homeless < 3 months ago but not currently | 0.76 (0.41–1.43) | 0.398 | ||
Homeless > 3 months ago | 0.63 (0.34–1.17) | 0.141 | ||
Total annual income | ||||
< $10,000 | 1.00 | |||
≥ $10,000 | 0.80 (0.52–1.23) | 0.300 | ||
Food Security | ||||
Not sufficient | 1.00 | |||
Sufficient | 1.02 (0.53–1.97) | 0.963 | ||
Physician diagnosed medical conditions | ||||
Opioid use disorder | ||||
No | 1.00 | |||
Yes | 0.52 (0.35–0.79) | 0.002 | ||
Stimulant use disorder | ||||
No | 1.00 | 1.00 | ||
Yes | 0.53 (0.34–0.83) | 0.006 | 0.68 (0.43–1.07) | 0.091 |
Alcohol use disorder | ||||
No | 1.00 | 1.00 | ||
Yes | 1.69 (1.07–2.67) | 0.024 | 2.23 (1.38–3.60) | 0.001 |
Anxiety | ||||
No | 1.00 | |||
Yes | 0.89 (0.54–1.45) | 0.632 | ||
Depression | ||||
No | 1.00 | |||
Yes | 0.69 (0.41–1.17) | 0.170 | ||
Cardiovascular disease | ||||
No | 1.00 | |||
Yes | 0.64 (0.39–1.06) | 0.085 | ||
Hepatitis C | ||||
No | 1.00 | |||
Yes | 0.73 (0.48–1.13) | 0.157 | ||
Asthma | ||||
No | 1.00 | 1.00 | ||
Yes | 0.37 (0.14-1.00) | 0.051 | 0.36 (0.13–1.02) | 0.055 |
Anxiety and depression scores | ||||
GAD-7 Anxiety score | ||||
< 10 (Minimal to mild) | 1.00 | |||
≥ 10 (Moderate to severe) | 0.86 (0.56–1.32) | 0.490 | ||
CES-D Depression score | ||||
< 10 | 1.00 | |||
≥ 10 (Significant symptoms) | 0.69 (0.10–1.66) | 0.078 | ||
Health Services Visits | ||||
Medical doctor visits | ||||
# per 3 months | 0.64 (0.56–0.73) | < 0.001 | 0.69 (0.60–0.79) | < 0.001 |
Social Worker visits | ||||
# per 3 months | 0.70 (0.58–0.86) | < 0.001 | 0.73 (0.59–0.90) | 0.003 |